By Carl Eisdorfer PhD MD
Big apple 1982 Springer. eightvo, 436pp., index, unique gilt revealed hardcover. VG, tiny chip on entrance, no DJ.
Read Online or Download Annual Review of Gerontology and Geriatrics, Volume 3, 1982: Clinical, Behavioral and Social Issues PDF
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Extra resources for Annual Review of Gerontology and Geriatrics, Volume 3, 1982: Clinical, Behavioral and Social Issues
117:2204. Nilsson, B. S. 1971. Reactivity to PPD and phyto-hemagglutin in relation to PPD skin reactivity and age. Scand. J. Resp. Dis. 52:39. Paul, J. , and Bunnell, W. W. 1932. Anti-SRBC aggultination with age. Am. J. Med. Sci. 183:90. , and Van Zwieten, M. J. 1980. Idiopathic paraproteinemia. III. Increased frequency of paraproteinemia in thymectomized aging C57BL/KaLwRij and CBA/BrRij mice. /. Immunol. 125:31. Roberts-Thompson, I. , Whittingham, S. , and MacKay, T. R. 1974. Ageing, immune response and mortality.
W. 1977. Ontogeny of B-lymphocyte function. III. In vivo and in vitro studies on the ease of tolerance induction to B lymphocytes from fetal, neonatal and adult mice. J. Exp. Med. 145:1590. Szewczuk, N. , Sherr, D. , and Siskind, G. W. 1978. Ontogeny of B lymphocyte function. VI. Ontogeny of thymus cell capacity to facilitate the functional maturation of B lymphocytes. Eur. J. Immunol. 8:370. Szewczuk, M. , DeKruyff, R. , Goidl, E. , Weksler, M. , and Siskind, G. W. 1980. Ontogeny of B lymphocyte function.
It seems possible that, in this way, the immune system acts to regulate itself. It should be emphasized that idiotype-specific regulatory interactions probably operate both at the T- and B-cell levels and at the serum antibody level. , 1980). , 1980). This down-regulation contributes to the apparent immune defect in aged mice. , 1980)—that is, the set of DNP-specific idiotypes produced by mice in response to DNP-Ficoll changes with age. This represents an additional age-related change in B-cell function and regulation.
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