July 16, 2017

Download Anticancer Agents. Frontiers in Cancer Chemotherapy by Iwao Ojima, Gregory D. Vite, Karl-Heinz Altmann PDF

By Iwao Ojima, Gregory D. Vite, Karl-Heinz Altmann

content material: melanoma drug discovery and improvement : new paradigms for a brand new millennium / E.A. Sausville ... [et al.] --
Evolutionary biosynthesis of anticancer medications / George R. Pettit --
a few contemporary advancements within the synthesis and structure-activity dating of novel taxanes / John F. Kadow ... [et al.] --
New new release taxoids and hybrids of microtubule-stabilizing anticancer brokers / Iwao Ojima ... [et al.] --
Discodermolide and taxol : a synergistic drug mix in human carcinoma mobilephone strains / Susan Band Horwitz ... [et al.] --
hugely effective semisynthesis of biologically energetic epothilone derivatives / Gregory D. Vite ... [et al.] --
man made and semisynthetic analogs of epothilones : chemistry and organic task / Karl-Heinz Altmann ... [et al.] --
Synthesis and organic task of epothilones / Ulrich Klar ... [et al.] --
Epothilones and sarcodictyins : from combinatorial libraries to designed analogs / Nicolas Winssinger and K.C. Nicolaou --
Synthesis and structure-activity courting stories of cryptophycins : a singular classification of effective antimitotic antitumor depsipeptides / Chuan Shih ... [et al.] --
Farnesyltransferase inhibitors as capability anticancer brokers / J.B. Gibbs ... [et al.] --
Farnesyltransferase inhibitors : from squalene synthase inhibitors to the scientific agent BMS-214662 / John T. Hunt --
Inhibiting farnesyl protein transferase with Sch-66336 : very likely a selective noncytotoxic remedy for human melanoma / A.G. Taveras ... [et al.] --
Pyrrolo[2,3-d]pyrimidine and pyrazolo[3,4-d]pyrimidine derivatives as selective inhibitors of the EGF receptor tryosine kinase / G. Caravatti ... [et al.] --
STI571 : a brand new therapy modality for CML? / Jürg Zimmermann, Pascal Furet, and Elisabeth Buchdunger --
the invention and improvement of second-generation matrix metalloproteinase inhibitors for the remedy of melanoma / Andy Baxter and John Montana --
customers for antiangiogenic treatments established upon VEGF inhibition / Pascal Furet and Paul W. Manley --
Carbohydrate-based tumor antigens as antitumor vaccine brokers / Jennifer R. Allen and Samuel J. Danishefsky --
medications to augment the healing efficiency of anticancer antibodies : antibody-drug conjugates as tumor-activated prodrugs / Walter A. Blättler and Ravi V.J. Chari.

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Singh, S. B . ; Hamel, E . ; L i n , C . ; Alberts, D . ; Garcia-Kendall, D . Experientia 1989, 45, 209-211. Pettit, G . ; Rhodes, M. Anti-Cancer Drug Des. 1998, 13, 183-191. Horsman, M. R . ; Ehrnrooth, E . ; Overgaard, J . Int. J. Radiation Oncology Biol. Phys. 1998, 42, 895-898. Dark, G . ; Hill, S. Α . ; Prise, V. ; Tozer, G . ; Pettit, G . R . ; Chaplin, D . J . Cancer Res. 1997, 57, 1829-1834. Chaplin, D . J . ; Pettit, G . ; Hill, S. A. Anticancer Res. 1999, 19, 189195. Stevenson, J. P .

40. 41. 42. 43. 44. 45. 46. 47. 48. 49. 50. 51. 52. 53. 54. 55. 56. 57. 58. ; Hatanaka, T . ; Tsuji, T . ; Tsuruo, T. Jpn. J. Cancer Res. 1999, 90, 1016-1025. ; Thunnissen, A - M . W . H . ; White, A . W . ; Walter, J . ; Cleverly, Κ. ; Salinas, P. C . ; Wu, Y . ; Biernat, J . ; K i m , S - H . ; Pettit, G . R. Chem. and Biol. 2000, 7, 51-63. Schultz, C . ; Link, Α . ; Zaharevitz, D . W . ; Gussio, R . ; Sausville, Ε. ; Kunick, C . J. Med. Chem. 1999, 42, 29092919. Sausville, Ε. ; Zaharevitz, D .

Angew. , Int. Ed. Engl. 1998, 37, 187-192. Hayward, M. ; Roth, R. ; Duffy, K . J . ; Dalko, P. ; Stevens, K . ; Kishi, Y. Angew. Chem. Int. Ed. Engl. 1998, 37, 192-196. Evans, D . ; Trotter, B . W . ; Coleman, P. J . ; Côté, B . ; Dias, L. ; Rajapakse, Η. ; Tyler, A . N. Tetrahedron 1999, 55, 8671-8726. Claffey, M. ; Hayes, C . J . ; Heathcock, C . H. J. Org. Chem. 1999, 64, 8267-8274. ; Guyot, M. Tetrahedron Lett. 2000, 41, 3349-3353. ; Wallace, D . J . ; Oballa, R. M. Tetrahedron Lett. 1998, 39, 8545-8548.

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